| Current Biology & Life Sciences Articles |
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Chemistry World May 9, 2008 Simon Hadlington |
All-in-one gene detection on a chip Scientists in Singapore have invented a tiny machine that can rapidly prepare, purify and genetically analyse blood or other biological samples in less than 20 minutes.  |
Chemistry World May 6, 2008 James Mitchell Crow |
Building Peptides From the Wrong End UK chemists have cracked a long-standing problem in peptide synthesis that has prevented amino acid chains being grown from both ends. The insight could open up efficient ways to make peptide-based drugs.  |
HHMI Bulletin May 2008 |
Teaching Young Biologists New Tricks Nontraditional, active-learning approaches to introductory science and math courses are being tried at colleges such as North Carolina State University and the Massachusetts Institute of Technology.  |
HHMI Bulletin May 2008 Tom Cech |
A Season of Change The Howard Hughes Medical Institute has just announced a major new program for highly talented, early career scientists.  |
HHMI Bulletin May 2008 Mitch Leslie |
Genetic Balancing Act Animals have evolved intricate ways to ensure that gene activity is the same in males and females despite the inherent imbalance of x chromosomes.  |
HHMI Bulletin May 2008 Robin Mejia |
Sources of Renewal As scientists learn more about how to produce and manipulate stem cells -- amid high expectations and close scrutiny -- no one is ready to choose one approach over the other.  |
HHMI Bulletin May 2008 Stuart L. Schreiber |
Small Molecules for Big Medicines To improve the odds of drug discovery, the author uses small molecule "bioprobes" to study the causes of diseases and find better therapeutic targets for drug companies to explore.  |
HHMI Bulletin May 2008 Ingfei Chen |
Know When to Fold 'Em Scientists have collected convincing data to explain exactly how the endoplasmic reticulum (ER) can determine whether a cell lives or dies.  |
HHMI Bulletin May 2008 Sarah C.P. Williams |
Freeze-Framing a Fidgety Molecule Dorothee Kern is changing the way scientists think about enzymes.  |
HHMI Bulletin May 2008 Terry Devitt |
Baring HIV's Dependencies By recognizing characteristics of HIV host cells, scientists will be provided with a deeper understanding of the virus and develop potential ways to thwart it.  |
HHMI Bulletin May 2008 Dennis Meredith |
Hearing Through the Din Receptors embedded in the ear's hair cells might explain mammals' selective hearing.  |
HHMI Bulletin May 2008 Sarah C.P. Williams |
Of Fish and Men The same gene drives skin color evolution in stickleback fish and humans.  |
HHMI Bulletin May 2008 Sarah C.P. Williams |
Fixing Fragile X Knocking out a single gene in neurons eliminates symptoms of fragile X syndrome in mice.  |
Chemistry World May 2, 2008 Richard Van Noorden |
Synthesis boost for HIV research Hopes for a new type of HIV therapy have been raised by the first chemical synthesis of a scarce plant compound which flushes the virus out of hiding.  |
Chemistry World May 1, 2008 Simon Hadlington |
Click chemistry illuminates embryo development US researchers have smuggled modified sugar molecules into a developing zebrafish embryo and then used 'click chemistry' to snap a fluorescent tag onto them to watch cells and tissues forming.  |
Chemistry World May 1, 2008 Rebecca Trager |
Blood Substitutes Pose Worrying Risks Oxygen-carrying blood substitutes currently in clinical trials are associated with a much higher likelihood of serious adverse events such as heart attack and death.  |
Chemistry World May 2008 Philip Ball i |
Pulling our strings There is much more to DNA than that elegant double helix. The author explores the twists and tangles of chromatin.  |
Chemistry World May 2008 Philip Ball |
The crucible When the going gets tough, the tough get sweet. There are many physiological responses to cold conditions, but one of the common strategies for insects is to fill their cells with sugar.  |
Chemistry World April 30, 2008 Lewis Brindley |
Chemical compass clue to migration mystery Trying to identify the mysterious innate compass that many animals use to navigate the globe, chemists at the University of Oxford, UK, have shown for the first time that the Earth's magnetic field can influence the outcome of a chemical reaction.  |
Chemistry World April 28, 2008 Victoria Gill |
Gene silencing gets fat A team of researchers in the US has developed fat-like nanoparticles that can carry fragments of RNA into cells, bring treatments based on gene silencing a step closer.  |
Chemistry World April 23, 2008 Jane Qiu |
Bitter melon yields sweet results for diabetes Researchers have identified active ingredients in the warty green fruit that could lead to new treatments for diabetes.  |
Wired April 21, 2008 Thomas Goetz |
Why Medicine Should Care Less About "Sick," More About "Normal" Predictive medicine relies on knowing ranges of normal values so that it can screen for results outside of this range early on. Unfortunately, funding organizations are not interested in what is normal.  |
Wired April 21, 2008 Rachel Swaby |
Chromosome, Proteome ... Decoding the DNA of '-omes' The genome alone can't explain how our bodies work. We need to decode a lot of other complex biological systems that regulate how we develop.  |
Chemistry World April 21, 2008 Pete Mitchel |
The hunt for metabolic biomarkers In the largest metabonomics study ever carried out, researchers have discovered strong correlations between individuals' blood pressure and the levels of certain metabolites in their urine.  |
Reactive Reports Issue 73 David Bradley |
Gator Aid It's perhaps not the first place you would think to search for superbug-beating antibiotics, but alligator's blood could be a great source of novel compounds that could defeat strains of bacteria resistant to conventional antibiotics.  |
Reactive Reports Issue 73 David Bradley |
Fake Bird Flu Chemists have developed a rapid technique for detecting fake Tamiflu, the mainstay medication for preventing and treating bird flu.  |
Chemistry World April 15, 2008 James Mitchell Crow |
Guessing Nature's Silica Secrets Chemists hoping to copy the way ocean-going organisms build intricate silica nanostructures have developed effective new mimics of two key biomolecules.  |
Chemistry World April 10, 2008 Sarah Houlton |
Radiotherapy Side-Effects Suppressed A new drug being developed by scientists at Cleveland BioLabs (CBLI) in the US may hold the key to protecting healthy cells from the effects of radiotherapy during cancer treatment.  |
Chemistry World April 10, 2008 Henry Nicholls |
Water Retains DNA Memory of Hidden Species A team of scientists has demonstrated that DNA profiling could be a quick, effective and relatively cheap alternative to finding new species of animal life.  |
Chemistry World April 9, 2008 Henry Nicholls |
How plants shudder at shade Scientists claim to have worked out how plants channel energy away from leaves and into spindly shoots, a natural but at-times infuriating response to a bit of shade. Plants are sensitive to the wavelength of light that's reaching them.  |
Chemistry World April 8, 2008 Lewis Brindley |
Nanofibers Reconnect Nerves Mice paralyzed by spinal injuries have been able to walk again thanks to a treatment developed by scientists in the US.  |
Chemistry World April 7, 2008 Simon Hadlington |
Polyketide ring mystery solved US researchers have worked out how some microbes produce polyketides - a class of polycyclic compounds that have antibiotic and anti-cancer properties but are difficult to manufacture.  |
Chemistry World April 3, 2008 Philip Ball |
Antibiotic-Eating Bacteria Found in Soil Scientists in the US have found that soil is full of bacteria that will feed and grow on antibiotics the very compounds created to kill them.  |
Chemistry World April 3, 2008 Lewis Brindley |
DNA Read in a Trice The prospect of treatments that are tailored to fit an individual's genetic makeup is a step closer thanks to technology unveiled by US scientists.  |
Chemistry World April 1, 2008 Lewis Brindley |
Easier Cancer Imaging with Raman A new imaging technique based on Raman spectroscopy has been used to illuminate tumors in mice with unprecedented precision.  |
Chemistry World April 1, 2008 Michael Gross |
Aluminium's Vaccine Boost Explained Researchers based in the Netherlands and Belgium have worked out how aluminium salts, used to boost the effectiveness of vaccines, stimulate the immune system.  |
HHMI Bulletin Feb 2008 |
Guided By His Inner Compass A look at the work of geneticist Mario Capecchi.  |
HHMI Bulletin Feb 2008 |
Parsing Peroxisones In the 1992 movie Lorenzo's Oil, Hollywood portrayed a supplement, the boy's namesake oil, as a miracle cure for ALD. The reality is more complicated.  |
HHMI Bulletin Feb 2008 |
Wit & Wisdom Randy Schekman's passion for science has prompted bold action, and his audaciousness has paid off.  |
HHMI Bulletin Feb 2008 Michael Salter |
An Alternate View of Chronic Pain Scientists whose work challenges wisdom often toil for years before their ideas catch on -- if ever.  |
HHMI Bulletin Feb 2008 Charles Shank |
An Eye For the Exciting Charles V. Shank, director of the Lawrence Berkeley National Laboratory, has said farewell to bureaucratic exigencies that limit scientific risk-taking.  |
HHMI Bulletin Feb 2008 Richard Saltus |
Cold Nights and Hot Chocolate A microbiologist's backyard winter experiment.  |
HHMI Bulletin Feb 2008 Lindsay Moran |
An Absorbing Mascot Some scientists dislike SpongeBob SquarePants for misinforming people about marine sponges while other scientists appreciate the attention to their research.  |
HHMI Bulletin Feb 2008 Jacqueline Ruttimann |
Bright Ideas From Down Below Finding fluorescent proteins in your local pet store.  |
HHMI Bulletin Feb 2008 Janice Hopkins Tanne |
From Sperm to Stem Cells A biologist's fascination with tumorigenesis has paid off in unexpected ways, thanks to an astute observation he made about a particularly unusual type of tumor.  |
HHMI Bulletin Feb 2008 Shelley DuBois |
Fighting Malaria On His Home Turf For Louis Schofield, the malaria problem in Papua New Guinea is more than a passing interest.  |
HHMI Bulletin Feb 2008 Lisa Seachrist Chiu |
AIDS: No Time for Complacency The year 2007 was a roller coaster for the HIV/AIDS community, with great strides and bitter disappointments in the fight against HIV.  |
HHMI Bulletin Feb 2008 |
Bedside Inspiration A new group of investigators tackles basic research questions by splitting time between the laboratory and the clinic.  |
HHMI Bulletin Feb 2008 |
Bringing Down Cancer's House of Cards Defining an elaborate yet fragile control pathway offers a new strategy for toppling many cancers.  |
HHMI Bulletin Feb 2008 Lisa Seachrist Chiu |
Legions of Hijackers The multi-layered success strategy behind this ingenious pathogen is beginning to unfold.  |
HHMI Bulletin Feb 2008 Lisa Seachrist Chiu |
Tick-Tock Goes a Bacterial Clock Researchers now better understand the "gears" on this unusual Circadian Clock.  |
HHMI Bulletin Feb 2008 Dennis Meredith |
From Marshmallows to Missiles Knockout yields clues to how sperm are perfected for penetration.  |
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